Question

A 64-year-old with first episode of nonsevere C. difficile infection (WBC 9,000/µL, creatinine 1.0 mg/dL) seeks therapy. Best initial treatment?

Accepted Answer

Fidaxomicin 200 mg PO BID × 10 days (preferred)

Answer

Metronidazole 500 mg PO TID × 10 days

Answer

Oral vancomycin 125 mg QID × 10 days (preferred)

Answer

Rifaximin 550 mg TID × 14 days

Answer

Fecal microbiota transplantation now

Practice question

A 64-year-old with first episode of nonsevere C. difficile infection (WBC 9,000/µL, creatinine 1.0 mg/dL) seeks therapy. Best initial treatment?