Question

A 30-year-old presents 36 hours after sexual exposure and requests HIV prevention. Rapid Ag/Ab negative, no symptoms. Best PEP regimen and timing?

Accepted Answer

Start within 48 hours: TDF/FTC + dolutegravir for 28 days

Answer

Start within 96 hours: TDF/FTC + raltegravir for 28 days

Answer

Start within 7 days: any 2-drug regimen

Answer

Wait for repeat testing at 1 week

Answer

Single-dose dolutegravir now

Practice question

A 30-year-old presents 36 hours after sexual exposure and requests HIV prevention. Rapid Ag/Ab negative, no symptoms. Best PEP regimen and timing?