Question

A 28-year-old pregnant patient (36 weeks) with GBS colonization and severe penicillin allergy has GBS isolate resistant to clindamycin. Appropriate intrapartum prophylaxis?

Accepted Answer

Vancomycin 20 mg/kg IV q8h (adjusted for renal function)

Answer

Cefazolin 2 g IV then 1 g q8h

Answer

Clindamycin 900 mg IV q8h regardless of susceptibility

Answer

No prophylaxis at term

Answer

Oral amoxicillin at onset of labor

Practice question

A 28-year-old pregnant patient (36 weeks) with GBS colonization and severe penicillin allergy has GBS isolate resistant to clindamycin. Appropriate intrapartum prophylaxis?