Question

A 40-year-old man with BMI 32 kg/m² and chronic GERD asks about long-term PPI safety. Which is the guideline-based approach?

Accepted Answer

Use lowest effective PPI dose; reassess need periodically; continue if clear indication

Answer

Stop all PPIs due to theoretical risks

Answer

Switch all patients to H2 blockers

Answer

Routine EGD annually to monitor for cancer

Answer

Double-dose PPI indefinitely for everyone

Practice question

A 40-year-old man with BMI 32 kg/m² and chronic GERD asks about long-term PPI safety. Which is the guideline-based approach?