Question

A 59-year-old with HFrEF (EF 28%) and no diabetes asks about SGLT2 inhibitors. What is the guideline-based role?

Accepted Answer

Indicated to reduce HF hospitalization and CV death regardless of diabetes

Answer

Not indicated without diabetes

Answer

Use only if intolerant to ACEI/ARB/ARNI

Answer

Use only for eGFR >90 mL/min/1.73 m²

Answer

Reserve for NYHA IV only

Practice question

A 59-year-old with HFrEF (EF 28%) and no diabetes asks about SGLT2 inhibitors. What is the guideline-based role?