Question

A 55-year-old man with nonvalvular AF and prior ischemic stroke asks about antithrombotic therapy. He has no mechanical valve or moderate-to-severe mitral stenosis. Best option?

Accepted Answer

A DOAC at stroke-prevention dose

Answer

Aspirin 325 mg daily

Answer

Warfarin due to prior stroke in all cases

Answer

Clopidogrel monotherapy

Answer

No therapy; bleeding risk precludes all anticoagulation

Practice question

A 55-year-old man with nonvalvular AF and prior ischemic stroke asks about antithrombotic therapy. He has no mechanical valve or moderate-to-severe mitral stenosis. Best option?