Question

A 62-year-old hospitalized patient develops first-episode nonsevere C. difficile infection (WBC 12,000/µL, creatinine 1.0 mg/dL). Optimal initial therapy?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Oral metronidazole 500 mg TID for 10 days

Answer

Oral vancomycin 125 mg QID for 10 days

Answer

Probiotics alone

Answer

IV vancomycin

Practice question

A 62-year-old hospitalized patient develops first-episode nonsevere C. difficile infection (WBC 12,000/µL, creatinine 1.0 mg/dL). Optimal initial therapy?