Question

A well-appearing 35-day-old infant has fever 101.8°F (38.8°C). Exam is normal. Labs: UA positive for leukocyte esterase and nitrites; WBC 8,600/µL; CRP low; hemodynamically stable and reliable follow-up is available. What is the recommended management?

Accepted Answer

Oral antibiotics for presumed UTI with outpatient follow-up

Answer

Full sepsis workup with LP and admit for IV ceftriaxone

Answer

Discharge without antibiotics; arrange next-day follow-up

Answer

Empiric IV antibiotics for 48 hours and mandatory LP

Answer

Single-dose IM ceftriaxone and no further therapy

Practice question

A well-appearing 35-day-old infant has fever 101.8°F (38.8°C). Exam is normal. Labs: UA positive for leukocyte esterase and nitrites; WBC 8,600/µL; CRP low; hemodynamically stable and reliable follow-up is available. What is the recommended management?