Question

A 66-year-old hospitalized patient develops watery diarrhea after 8 days of clindamycin. WBC 12,000/µL, creatinine 1.1 mg/dL; stool NAAT positive for C. difficile. What is the preferred initial therapy?

Accepted Answer

Fidaxomicin 200 mg BID for 10 days (preferred)

Answer

Oral vancomycin 125 mg QID for 10 days (only)

Answer

Metronidazole 500 mg TID for 10 days

Answer

Tigecycline IV

Answer

Fecal microbiota transplantation

Practice question

A 66-year-old hospitalized patient develops watery diarrhea after 8 days of clindamycin. WBC 12,000/µL, creatinine 1.1 mg/dL; stool NAAT positive for C. difficile. What is the preferred initial therapy?