Question

A 64-year-old hospitalized patient has a first episode of non-severe Clostridioides difficile infection (stool WBC <15,000/µL, creatinine normal). Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Oral metronidazole 500 mg TID for 10 days

Answer

Tapered oral vancomycin regimen

Answer

Probiotics alone

Answer

Bezlotoxumab monotherapy

Practice question

A 64-year-old hospitalized patient has a first episode of non-severe Clostridioides difficile infection (stool WBC <15,000/µL, creatinine normal). Best initial therapy?