Question

A 38-year-old woman with BMI 31 kg/m² and prediabetes (A1C 6.0%) seeks weight loss. BP 126/78. Which pharmacotherapy has demonstrated cardiovascular and weight benefits and is appropriate if lifestyle alone fails?

Accepted Answer

GLP-1 receptor agonist (e.g., semaglutide)

Answer

Orlistat

Answer

Phentermine monotherapy long-term

Answer

Thyroid hormone

Answer

Metformin is first-line for weight loss

Practice question

A 38-year-old woman with BMI 31 kg/m² and prediabetes (A1C 6.0%) seeks weight loss. BP 126/78. Which pharmacotherapy has demonstrated cardiovascular and weight benefits and is appropriate if lifestyle alone fails?