Question

A 72-year-old man with nonvalvular atrial fibrillation, hypertension, and type 2 diabetes has an eGFR of 65 mL/min/1.73 m². His CHA₂DS₂-VASc score is 4. What is the most appropriate next step to reduce stroke risk?

Accepted Answer

Start a direct oral anticoagulant

Answer

No antithrombotic therapy because bleeding risk is unknown

Answer

Aspirin 81 mg daily

Answer

Warfarin with target INR 1.5-2.0

Answer

Clopidogrel 75 mg daily

Practice question

A 72-year-old man with nonvalvular atrial fibrillation, hypertension, and type 2 diabetes has an eGFR of 65 mL/min/1.73 m². His CHA₂DS₂-VASc score is 4. What is the most appropriate next step to reduce stroke risk?