Question

A 64-year-old man with recurrent gout has urate 520 µmol/L between attacks. Best timing and target for urate-lowering therapy?

Accepted Answer

Start allopurinol 2-4 weeks after flare resolves; target <360 µmol/L

Answer

Start allopurinol during acute flare; target <500 µmol/L

Answer

Start febuxostat only if CKD; target <300 µmol/L

Answer

Avoid long-term therapy; diet only

Answer

Use probenecid routinely

Practice question

A 64-year-old man with recurrent gout has urate 520 µmol/L between attacks. Best timing and target for urate-lowering therapy?