Question

A 70-year-old man with osteoarthritis of the knee has persistent pain not controlled by paracetamol and topical NSAIDs. He has a history of peptic ulcer disease and is on omeprazole. What is the most appropriate next pharmacological step?

Accepted Answer

Start oral naproxen with PPI cover

Answer

Start oral ibuprofen without gastroprotection

Answer

Start oral diclofenac without PPI

Answer

Start oral codeine phosphate alone

Answer

Intra-articular steroid without analgesia change

Practice question

A 70-year-old man with osteoarthritis of the knee has persistent pain not controlled by paracetamol and topical NSAIDs. He has a history of peptic ulcer disease and is on omeprazole. What is the most appropriate next pharmacological step?