Question

A 64-year-old man with T2DM (HbA1c 67 mmol/mol) and BMI 33 kg/m² is on metformin maximum tolerated dose. eGFR 72. No ASCVD. What is the most appropriate second-line agent prioritising weight loss and cardiovascular risk reduction?

Accepted Answer

SGLT2 inhibitor (empagliflozin)

Answer

Sulfonylurea (gliclazide)

Answer

DPP-4 inhibitor (sitagliptin)

Answer

Pioglitazone

Answer

Basal insulin

Practice question

A 64-year-old man with T2DM (HbA1c 67 mmol/mol) and BMI 33 kg/m² is on metformin maximum tolerated dose. eGFR 72. No ASCVD. What is the most appropriate second-line agent prioritising weight loss and cardiovascular risk reduction?