Question

A 67-year-old with type 2 diabetes, albuminuric CKD (uACR 45 mg/mmol) and prior MI is on metformin. HbA1c is 62 mmol/mol. Which agent provides renal and cardiovascular benefit as next step?

Accepted Answer

SGLT2 inhibitor (e.g., empagliflozin)

Answer

DPP-4 inhibitor (e.g., sitagliptin)

Answer

Sulfonylurea (e.g., gliclazide)

Answer

Basal insulin

Answer

Thiazolidinedione (pioglitazone)

Practice question

A 67-year-old with type 2 diabetes, albuminuric CKD (uACR 45 mg/mmol) and prior MI is on metformin. HbA1c is 62 mmol/mol. Which agent provides renal and cardiovascular benefit as next step?