Question

A 76-year-old woman with non-valvular atrial fibrillation (CHA₂DS₂-VASc 4, weight 68 kg, eGFR 52 mL/min/1.73m²) requires stroke prevention. Which is the most appropriate first-line anticoagulant?

Accepted Answer

Apixaban 5 mg twice daily

Answer

Warfarin with INR target 3.5

Answer

Aspirin 75 mg daily

Answer

Dabigatran 150 mg twice daily despite age

Answer

No anticoagulation as HAS-BLED is 3

Practice question

A 76-year-old woman with non-valvular atrial fibrillation (CHA₂DS₂-VASc 4, weight 68 kg, eGFR 52 mL/min/1.73m²) requires stroke prevention. Which is the most appropriate first-line anticoagulant?