Question

A patient taking an ACE inhibitor for hypertension develops swelling of her lips and tongue. There is no urticaria or pruritus. What is the underlying mechanism of this adverse reaction?

Accepted Answer

Bradykinin accumulation

Answer

IgE-mediated mast cell degranulation

Answer

Direct histamine release

Answer

Type IV hypersensitivity reaction

Answer

Immune complex deposition

Practice question

A patient taking an ACE inhibitor for hypertension develops swelling of her lips and tongue. There is no urticaria or pruritus. What is the underlying mechanism of this adverse reaction?