Practice question

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A 70-year-old man with heart failure with reduced ejection fraction (HFrEF, LVEF 30%) is stable on Ramipril 10mg OD and Bisoprolol 7.5mg OD. He remains symptomatic (NYHA Class II). His potassium is 4.5 mmol/L and eGFR is 50 mL/min/1.73m². What is the next essential disease-modifying drug class to add?

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