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MediumCardiologyHeart Failure with Reduced Ejection Fraction (HFrEF)ukmlamrcgp aktpanemrcem sbamrcp part 1prescribing safety assessment

A 62-year-old man presents with worsening exertional dyspnoea and orthopnoea. Echocardiogram shows a left ventricular ejection fraction (LVEF) of 35%. He is euvolaemic. Which two medications should be initiated first-line (sequentially or together) to improve prognosis?

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