Practice question

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A 34-year-old woman presents with a 6-week history of intermittent bloody diarrhoea, abdominal cramps, and urgency. She also reports feeling fatigued. A colonoscopy reveals continuous inflammation from the rectum extending proximally to the splenic flexure, with loss of vascular pattern and friability. Biopsies show crypt abscesses and goblet cell depletion. What is the most likely diagnosis?

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