Question

A 25-year-old patient with known Crohn's disease, currently managed with mesalazine, presents with an acute flare-up characterised by 8 bloody stools per day, abdominal pain, and a temperature of 38.2°C. What is the most appropriate initial pharmacological management for this acute severe flare?

Accepted Answer

Intravenous hydrocortisone

Answer

Oral prednisolone 40mg daily

Answer

Oral budesonide 9mg daily

Answer

Continue mesalazine and add loperamide

Answer

Switch to adalimumab

Practice question

A 25-year-old patient with known Crohn's disease, currently managed with mesalazine, presents with an acute flare-up characterised by 8 bloody stools per day, abdominal pain, and a temperature of 38.2°C. What is the most appropriate initial pharmacological management for this acute severe flare?