Question

A 58-year-old woman with known rheumatoid arthritis, well-controlled on methotrexate 15mg weekly and folic acid, presents for her routine blood monitoring. Which of the following results would be the most significant concern requiring immediate action regarding her methotrexate?

Accepted Answer

White cell count 2.5 x 10^9/L (4.0-11.0)

Answer

Haemoglobin 105 g/L (115-165)

Answer

Platelets 130 x 10^9/L (150-400)

Answer

ALT 70 U/L (<40)

Answer

Creatinine 110 µmol/L (60-100)

Practice question

A 58-year-old woman with known rheumatoid arthritis, well-controlled on methotrexate 15mg weekly and folic acid, presents for her routine blood monitoring. Which of the following results would be the most significant concern requiring immediate action regarding her methotrexate?