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MediumInfectious DiseasesUTI in CKDukmlamrcgp aktpaneprescribing safety assessment

A 62-year-old woman with type 2 diabetes and CKD stage 3 (eGFR 48 mL/min/1.73m$^2$) presents with symptoms suggestive of a UTI. MSU confirms E. coli infection sensitive to nitrofurantoin, trimethoprim, and cefalexin. Which is the most appropriate antibiotic choice, considering her renal function?

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