Question

A patient with moderate knee osteoarthritis and Chronic Kidney Disease stage 3b (eGFR 35 ml/min/1.73m²) finds Paracetamol 1g QDS insufficient for pain relief. According to NICE guidelines on osteoarthritis, what is the most appropriate next step to consider for pharmacological management?

Accepted Answer

Offer a trial of topical NSAID or topical Capsaicin

Answer

Add regular oral Ibuprofen 400mg TDS

Answer

Add regular oral Naproxen 500mg BD

Answer

Add Codeine phosphate 30mg QDS PRN

Answer

Refer for intra-articular steroid injection

Practice question

A patient with moderate knee osteoarthritis and Chronic Kidney Disease stage 3b (eGFR 35 ml/min/1.73m²) finds Paracetamol 1g QDS insufficient for pain relief. According to NICE guidelines on osteoarthritis, what is the most appropriate next step to consider for pharmacological management?