Question

A 68-year-old ex-smoker with a 40-pack-year history presents with chronic cough and sputum production. Spirometry shows FEV1/FVC <0.7. He experiences frequent exacerbations. According to NICE, which initial pharmacological therapy is recommended?

Accepted Answer

Long-acting beta-2 agonist plus long-acting muscarinic antagonist

Answer

High-dose inhaled corticosteroid alone

Answer

Short-acting beta-2 agonist alone

Answer

Oral theophylline

Answer

Long-term oral corticosteroids

Practice question

A 68-year-old ex-smoker with a 40-pack-year history presents with chronic cough and sputum production. Spirometry shows FEV1/FVC <0.7. He experiences frequent exacerbations. According to NICE, which initial pharmacological therapy is recommended?