A patient with advanced HIV starts antiretroviral therapy during treatment for disseminated tuberculosis. Two weeks later fever, lymph-node enlargemen...

Question

A patient with advanced HIV starts antiretroviral therapy during treatment for disseminated tuberculosis. Two weeks later fever, lymph-node enlargement and inflammatory lung infiltrates worsen despite falling HIV viral load and adherence. What is the most likely explanation?

Accepted Answer

Paradoxical immune reconstitution inflammatory syndrome

Answer

Early virological failure of antiretroviral treatment

Answer

New Pneumocystis pneumonia during immune recovery

Answer

Drug-induced lupus caused by isoniazid treatment

Answer

Persistent tuberculosis from antimicrobial malabsorption

HIV — MRCP Part 1 MCQ

A patient with advanced HIV starts antiretroviral therapy during treatment for disseminated tuberculosis. Two weeks later fever, lymph-node enlargement and inflammatory lung infiltrates worsen despite falling HIV viral load and adherence. What is the most likely explanation?