Question

A 42-year-old man with treated acromegaly complains of persistent symptoms. His IGF-1 levels remain elevated. He is already on maximum tolerated dose of somatostatin analogues. What is the recommended next therapeutic step?

Accepted Answer

Add pegvisomant

Answer

Add bromocriptine

Answer

Transsphenoidal surgery

Answer

External beam radiotherapy immediately

Answer

Stop all therapy and observe

Practice question

A 42-year-old man with treated acromegaly complains of persistent symptoms. His IGF-1 levels remain elevated. He is already on maximum tolerated dose of somatostatin analogues. What is the recommended next therapeutic step?