Question

A 30-year-old woman presents with symmetrical small joint pain in her hands, stiffness in the morning lasting over an hour. Which antibody is most specific for the likely diagnosis?

Accepted Answer

Anti-cyclic citrullinated peptide (anti-CCP)

Answer

Antinuclear antibodies (ANA)

Answer

Anti-double-stranded DNA (anti-dsDNA)

Answer

Rheumatoid factor (RF)

Answer

Antimitochondrial antibodies (AMA)

Practice question

A 30-year-old woman presents with symmetrical small joint pain in her hands, stiffness in the morning lasting over an hour. Which antibody is most specific for the likely diagnosis?