Question

A 72-year-old woman presents with a resting tremor, bradykinesia, and rigidity consistent with Parkinson's disease. She has mild functional impairment. According to NICE guidelines, which medication class can be offered as initial therapy to improve motor symptoms?

Accepted Answer

Levodopa/carbidopa

Answer

Anticholinergics (e.g., trihexyphenidyl)

Answer

Amantadine

Answer

Monoamine oxidase-B inhibitor (e.g., selegiline)

Answer

COMT inhibitor (e.g., entacapone)

Practice question

A 72-year-old woman presents with a resting tremor, bradykinesia, and rigidity consistent with Parkinson's disease. She has mild functional impairment. According to NICE guidelines, which medication class can be offered as initial therapy to improve motor symptoms?