Question

A 65-year-old patient with advanced COPD has multiple exacerbations despite optimal inhaled therapy (long-acting beta-2 agonist plus long-acting muscarinic antagonist). Which of the following is recommended by NICE for patients who remain at high risk of exacerbations?

Accepted Answer

Macrolide antibiotic prophylaxis (e.g., azithromycin)

Answer

Roflumilast

Answer

Long-term oral corticosteroids

Answer

Theophylline

Answer

Leukotriene receptor antagonist

Practice question

A 65-year-old patient with advanced COPD has multiple exacerbations despite optimal inhaled therapy (long-acting beta-2 agonist plus long-acting muscarinic antagonist). Which of the following is recommended by NICE for patients who remain at high risk of exacerbations?