Question

A 70-year-old patient presenting with fatigue and weight loss is found to have leukocytosis with predominantly mature lymphocytes, smudge cells on peripheral smear, and splenomegaly. What is the most likely diagnosis?

Accepted Answer

Chronic lymphocytic leukaemia (CLL)

Answer

Chronic myeloid leukaemia (CML)

Answer

Acute lymphoblastic leukaemia (ALL)

Answer

Acute myeloid leukaemia (AML)

Answer

Hairy cell leukaemia

Practice question

A 70-year-old patient presenting with fatigue and weight loss is found to have leukocytosis with predominantly mature lymphocytes, smudge cells on peripheral smear, and splenomegaly. What is the most likely diagnosis?