Question

A 63-year-old woman with established rheumatoid arthritis and persistent synovitis on methotrexate therapy is being considered for a biologic DMARD. Which test must be done before initiating TNF inhibitor therapy?

Accepted Answer

Screening for latent tuberculosis (e.g., Mantoux or IGRA)

Answer

Autoantibody panel

Answer

Serum calcium level

Answer

Thyroid function tests

Answer

Genetic testing for HLA-B27

Practice question

A 63-year-old woman with established rheumatoid arthritis and persistent synovitis on methotrexate therapy is being considered for a biologic DMARD. Which test must be done before initiating TNF inhibitor therapy?