Question

A 28-year-old man with Crohn's disease presents with persistent diarrhoea and abdominal pain. He has been on oral steroids for 6 weeks but is not improving. According to NICE, which is the next best step in management for moderate to severe Crohn's disease unresponsive to steroids?

Accepted Answer

Azathioprine or mercaptopurine

Answer

5-aminosalicylic acid (5-ASA)

Answer

Metronidazole

Answer

High-fibre diet alone

Answer

Immediate surgery

Practice question

A 28-year-old man with Crohn's disease presents with persistent diarrhoea and abdominal pain. He has been on oral steroids for 6 weeks but is not improving. According to NICE, which is the next best step in management for moderate to severe Crohn's disease unresponsive to steroids?