Question

A 42-year-old woman presents with symmetrical joint stiffness in her hands lasting over an hour each morning. Rheumatoid arthritis is suspected. According to NICE, which investigation is most specific for rheumatoid arthritis?

Accepted Answer

Anti-cyclic citrullinated peptide (anti-CCP) antibodies

Answer

Rheumatoid factor (RF)

Answer

Anti-nuclear antibodies (ANA)

Answer

Erythrocyte sedimentation rate (ESR)

Answer

C-reactive protein (CRP)

Practice question

A 42-year-old woman presents with symmetrical joint stiffness in her hands lasting over an hour each morning. Rheumatoid arthritis is suspected. According to NICE, which investigation is most specific for rheumatoid arthritis?