Question

A 65-year-old patient with unexplained weight loss and severe back pain is found to have an elevated total protein and a monoclonal protein spike (M-spike) on serum protein electrophoresis. Which diagnosis is most likely?

Accepted Answer

Multiple myeloma

Answer

Chronic lymphocytic leukaemia

Answer

Non-Hodgkin lymphoma

Answer

Waldenström macroglobulinaemia

Answer

Acute myeloid leukaemia

Practice question

A 65-year-old patient with unexplained weight loss and severe back pain is found to have an elevated total protein and a monoclonal protein spike (M-spike) on serum protein electrophoresis. Which diagnosis is most likely?