Question

A 45-year-old man complains of a persistent cough. He is found to have TB requiring a rifampicin-based regimen. Which key interaction is important to counsel about?

Accepted Answer

Rifampicin reduces the effect of warfarin by inducing metabolism

Answer

Rifampicin increases INR in warfarin therapy

Answer

Rifampicin has no effect on oral contraceptives

Answer

Rifampicin is a potent CYP450 inhibitor

Answer

Rifampicin does not affect steroid metabolism

Practice question

A 45-year-old man complains of a persistent cough. He is found to have TB requiring a rifampicin-based regimen. Which key interaction is important to counsel about?