Question

A 65-year-old man has back pain and an elevated serum calcium level. Further tests show a monoclonal protein spike on serum electrophoresis (M-spike) and Bence Jones proteinuria. Which diagnosis is most likely?

Accepted Answer

Multiple myeloma

Answer

Osteoarthritis

Answer

Metastatic prostate cancer

Answer

Waldenström's macroglobulinaemia

Answer

Chronic lymphocytic leukaemia

Practice question

A 65-year-old man has back pain and an elevated serum calcium level. Further tests show a monoclonal protein spike on serum electrophoresis (M-spike) and Bence Jones proteinuria. Which diagnosis is most likely?