Question

A 55-year-old obese patient with type 2 diabetes mellitus has an HbA1c of 65 mmol/mol (8.1%). He is currently on metformin alone. According to NICE guidelines, what is the recommended second-line therapy if weight loss is a priority?

Accepted Answer

GLP-1 receptor agonist (e.g., liraglutide)

Answer

Sulfonylurea (e.g., gliclazide)

Answer

DPP-4 inhibitor (e.g., sitagliptin)

Answer

Insulin therapy

Answer

Thiazolidinedione (e.g., pioglitazone)

Practice question

A 55-year-old obese patient with type 2 diabetes mellitus has an HbA1c of 65 mmol/mol (8.1%). He is currently on metformin alone. According to NICE guidelines, what is the recommended second-line therapy if weight loss is a priority?