Question

A 55-year-old obese patient with polyuria, polydipsia, and fasting glucose of 8.0 mmol/L is diagnosed with type 2 diabetes mellitus. According to NICE guidelines, what is the first-line pharmacological therapy if lifestyle modifications are insufficient?

Accepted Answer

Metformin

Answer

Insulin

Answer

Sulfonylurea (e.g., gliclazide)

Answer

DPP-4 inhibitor (e.g., sitagliptin)

Answer

GLP-1 agonist (e.g., liraglutide)

Practice question

A 55-year-old obese patient with polyuria, polydipsia, and fasting glucose of 8.0 mmol/L is diagnosed with type 2 diabetes mellitus. According to NICE guidelines, what is the first-line pharmacological therapy if lifestyle modifications are insufficient?