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Diagnostic criteria for T2DM (HbA1c, fasting glucose, OGTT)?
Answer
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 10 December 2025
Diagnostic criteria for type 2 diabetes mellitus based on HbA1c, fasting blood glucose, and oral glucose tolerance test (OGTT) results are as follows:
- HbA1c level of 6.5% (48 mmol/mol) or above indicates a diagnosis of type 2 diabetes in adults who are not pregnant.
- Fasting venous plasma glucose concentration of 7.0 mmol/l or greater is diagnostic of type 2 diabetes.
- Two-hour venous plasma glucose concentration of 11.1 mmol/l or greater after a 75 g anhydrous glucose load in an OGTT confirms the diagnosis.
- Alternatively, a random venous plasma glucose concentration of 11.1 mmol/l or greater in the presence of symptoms can also be diagnostic.
- In asymptomatic patients, the diagnosis should be confirmed by repeating the test using World Health Organization criteria.
These criteria apply to adults who are not pregnant and are based on NICE guidelines and WHO recommendations.
Key References
- PH35 - Type 2 diabetes prevention: population and community-level interventions
- NG3 - Diabetes in pregnancy: management from preconception to the postnatal period
- CKS - Type 1 diabetes
- CKS - Diabetes - type 1
- CKS - Diabetes - type 2
- NG17 - Type 1 diabetes in adults: diagnosis and management
- CKS - Type 2 diabetes
- NG28 - Type 2 diabetes in adults: management
- Tolbutamide SmPC
- Glimepiride SmPC
- Lixisenatide SmPC
- Glipizide SmPC
- Glibenclamide SmPC
- Gliclazide SmPC
- Liraglutide SmPC
- Dulaglutide SmPC
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