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Asthma current guidelines
Answer
Initial assessment and diagnosis: Asthma diagnosis requires a suggestive clinical history (wheeze, cough, breathlessness, chest tightness, symptom variability) supported by objective tests; diagnosis should not be confirmed without both 2. Physical examination may identify wheeze but a normal exam does not exclude asthma 2.
Initial treatment: For people aged 12 and over with newly diagnosed asthma, offer a low-dose inhaled corticosteroid (ICS)/formoterol combination inhaler as needed for symptom relief (anti-inflammatory reliever [AIR] therapy) 1. If symptoms are frequent or severe, offer low-dose maintenance and reliever therapy (MART) with ICS/formoterol 1. For children under 5, start with low-dose ICS for 8–12 weeks as empirical treatment, with specialist referral if diagnosis is uncertain or asthma is uncontrolled 1.
Self-management and education: Provide advice on self-care, avoidance of triggers, smoking cessation, weight management, regular physical activity, stress management, and ensure vaccinations are up to date 1. A personalised asthma action plan should be provided and reviewed regularly 1,2.
Monitoring: Review asthma control at least annually and after exacerbations, using symptom questionnaires and clinical assessment; routine peak expiratory flow monitoring is not recommended unless personalised 2. Fractional exhaled nitric oxide (FeNO) monitoring may be considered in adults 2.
Stepping up and down treatment: Step up treatment if control is suboptimal, considering MART or adding leukotriene receptor antagonists (LTRA) in children if MART is not suitable 1,2. Step down treatment after 8–12 weeks of good control, maintaining the minimum effective ICS dose, with instructions on how to restart if symptoms worsen 1.
Specialist referral: Refer to asthma specialists if diagnosis is uncertain, asthma is uncontrolled despite treatment, or occupational asthma is suspected 2.
Pregnancy: Continue ICS-containing treatment during pregnancy to reduce risk of exacerbations and adverse perinatal outcomes 1.
Key References
- CKS - Asthma
- NG245 - Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN)
- Theophylline SmPC
- Formoterol fumarate SmPC
- Reslizumab SmPC
- Mepolizumab SmPC
- Salmeterol SmPC
- Budesonide with formoterol SmPC
- Tiotropium SmPC
- Ciclesonide SmPC
- NG115 - Chronic obstructive pulmonary disease in over 16s: diagnosis and management
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