How to assess community-acquired pneumonia severity and choose treatment in prim

Clinical answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 September 2025Updated: 16 September 2025 Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Assessment of severity: In primary care, the severity of community-acquired pneumonia (CAP) should be assessed using the CRB65 scoring system, which assigns 1 point each for confusion, respiratory rate ≥30 breaths/min, low blood pressure (systolic <90 mmHg or diastolic ≤60 mmHg), and age ≥65 years.

Patients are stratified by mortality risk: 0 points indicate low risk (<1% mortality), 1-2 points intermediate risk (1-10%), and 3-4 points high risk (>10%).

Clinical judgement should be used alongside the CRB65 score, considering factors such as comorbidities or pregnancy.

Management decisions based on CRB65: Consider hospital assessment for patients with a CRB65 score of 2 or more.

For those with a score of 1, discuss care options and make a shared decision, which may include supported home-based care.

Patients with a score of 0 can generally be managed with home-based care.

Treatment selection: Antibiotic prescribing should follow NICE antimicrobial guidelines for community-acquired pneumonia.

Microbiological tests are not routinely required in low-severity cases.

Point-of-care C-reactive protein (CRP) testing may support antibiotic decisions if clinical uncertainty exists: immediate antibiotics if CRP >100 mg/L, consider back-up prescription if CRP 20-100 mg/L, and no antibiotics if CRP <20 mg/L.

Patients should be advised to seek further medical advice if symptoms worsen or do not improve as expected.

Educational content only. Always verify information and use clinical judgement.

How to assess community-acquired pneumonia severity and choose treatme