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What are the recommended fluid resuscitation protocols for managing hypovolemic shock in adults?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 22 August 2025

Recommended fluid resuscitation protocols for managing hypovolemic shock in adult patients:

  • Initial assessment should identify hypovolemia using clinical indicators such as systolic blood pressure less than 100 mmHg, heart rate over 90 bpm, capillary refill time over 2 seconds or cold peripheries, respiratory rate over 20 breaths per minute, and a National Early Warning Score (NEWS) of 5 or more. Passive leg raising can be used to assess fluid responsiveness at the bedside 3.
  • For fluid resuscitation, intravenous (IV) fluids should be administered promptly to patients who cannot meet their fluid needs orally or enterally, with continuous reassessment and monitoring 3.
  • In cases of hypovolemic shock due to active bleeding (haemorrhagic shock), hospital protocols recommend avoiding crystalloids and instead using blood components with a ratio of 1 unit plasma to 1 unit red blood cells for adults 2.
  • In pre-hospital settings, crystalloids may be used to replace fluid volume if blood components are unavailable, but in hospital settings, blood components are preferred for active bleeding 2.
  • For non-bleeding hypovolemic shock, follow the NICE guideline on intravenous fluid therapy in adults, which includes using isotonic crystalloid solutions for initial resuscitation, titrated to clinical response and ongoing monitoring 3.
  • Continuous monitoring during resuscitation should include ABCDE assessment, respiratory rate, pulse, blood pressure, perfusion, venous lactate, arterial pH, and base excess as per advanced life support guidance 3.
  • Fluid prescriptions must specify type, rate, and volume, and patients should have an IV fluid management plan with daily expert review initially 3.

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This content was generated by iatroX. Always verify information and use clinical judgment.