When should I consider referring a patient with orbital cellulitis to secondary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Consider referring a patient with orbital cellulitis to secondary care urgently if there are signs of severe infection, visual impairment, or systemic symptoms. This includes any evidence of new-onset squint with neurological signs such as ataxia, vomiting, or headache, which require immediate referral to acute paediatric services if the patient is a child. Additionally, paralytic squint warrants urgent neurological assessment. Non-paralytic squint should be referred to ophthalmology services. These signs may indicate orbital involvement or complications requiring specialist management.

In general, orbital cellulitis is a serious condition that often necessitates secondary care assessment for intravenous antibiotics, imaging, and specialist ophthalmology input to prevent vision loss or intracranial complications.

Educational content only. Always verify information and use clinical judgement.