What are the key management strategies for a patient with diabetic ketoacidosis presenting in primary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Key management strategies for a patient presenting with diabetic ketoacidosis (DKA) in primary care include:

  • Immediate recognition and suspicion of DKA: Suspect DKA in any patient with diabetes presenting with symptoms such as nausea, vomiting, abdominal pain, hyperventilation, dehydration, or reduced consciousness, even if blood glucose is normal, especially in children and young people on insulin therapy .
  • Urgent hospital referral: Patients suspected of having DKA must be sent immediately to a hospital with appropriate acute facilities for urgent assessment and treatment; DKA cannot be managed safely in primary care .
  • Ketone measurement if available: If near-patient blood ketone testing (beta-hydroxybutyrate) is available, measure ketones to support diagnosis; if elevated or if testing is unavailable, urgent hospital referral is mandatory .
  • Explain seriousness and need for urgent care: Inform the patient and their family or carers that DKA is a serious condition requiring urgent hospital assessment .
  • Do not initiate treatment beyond basic supportive measures: In primary care, do not attempt intravenous fluids or insulin therapy; these require hospital-based monitoring and specialist care .

In summary, the key management strategy in primary care is prompt recognition of DKA and immediate urgent referral to hospital for definitive management, supported by ketone testing if available and clear communication about the seriousness of the condition ,.

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