Referral criteria for suspected systemic mastocytosis: There are no specific referral criteria for systemic mastocytosis detailed in the provided UK suspected cancer referral guidelines. However, systemic mastocytosis is a rare haematological disorder that may present with symptoms such as unexplained skin lesions, pruritus, anaphylaxis, or systemic symptoms including weight loss, night sweats, or lymphadenopathy. Given these features overlap with haematological malignancies, patients suspected of systemic mastocytosis should be referred urgently for specialist haematology assessment.
Specialist referral: Patients suspected of having systemic mastocytosis should be referred to a haematologist for further evaluation and diagnosis, as systemic mastocytosis is classified as a myeloproliferative neoplasm and requires specialist haematological expertise.