How should I assess the nutritional status of a patient who presents with unintentional weight loss?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Assessing the nutritional status of a patient with unintentional weight loss involves:

  • Screening for malnutrition using tools such as the Malnutrition Universal Screening Tool (MUST), which includes measuring body mass index (BMI) and calculating the percentage of unintentional weight loss over time.
  • Considering the duration and extent of reduced nutrient intake, including whether the patient has eaten little or nothing for more than 5 days or is likely to continue this pattern.
  • Evaluating clinical signs of malnutrition such as fragile skin, poor wound healing, muscle wasting, poor appetite, altered taste sensation, and swallowing difficulties.
  • Using specific criteria to identify malnutrition: a BMI less than 18.5 kg/m², unintentional weight loss greater than 10% within the last 3 to 6 months, or a BMI less than 20 kg/m² with unintentional weight loss greater than 5% within the last 3 to 6 months.
  • Monitoring anthropometric parameters such as weight, BMI, mid-arm circumference, and triceps skinfold thickness regularly to assess ongoing nutritional status.
  • Considering the need for further investigations or referrals if weight loss is unexplained or associated with other symptoms suggestive of serious underlying conditions, including cancer.

These steps ensure a comprehensive assessment of nutritional status and help guide appropriate nutrition support interventions if needed.

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Educational content only. Always verify information and use clinical judgement.