What are the recommended management strategies for a patient with mild SLE symptoms in primary care?

In primary care, management of a patient with mild systemic lupus erythematosus (SLE) symptoms should focus on symptom control, prevention of disease progression, and regular monitoring. Initial strategies include patient education about the disease, avoidance of known triggers such as ultraviolet light, and lifestyle modifications including smoking cessation and balanced diet to reduce cardiovascular risk factors. Symptomatic treatment with non-steroidal anti-inflammatory drugs (NSAIDs) may be used cautiously for musculoskeletal symptoms, while hydroxychloroquine is recommended as a first-line disease-modifying agent due to its efficacy in controlling mild disease and preventing flares. Regular monitoring of disease activity and organ involvement is essential, with prompt referral to rheumatology if symptoms worsen or systemic involvement develops. Additionally, vaccination status should be reviewed and updated as appropriate to reduce infection risk. Psychological support and assessment for fatigue and mood disorders are also important components of holistic care in mild SLE. This integrated approach aligns with UK clinical guidelines emphasizing early intervention and multidisciplinary care ¹, while Lam et al. (2016) highlight the importance of hydroxychloroquine and vigilant monitoring in primary care to optimize outcomes and reduce complications (Lam et al., 2016).