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Which diagnostic tests are recommended for evaluating suspected non-allergic food sensitivities in adults?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 22 August 2025

For evaluating suspected non-allergic food sensitivities (non-IgE-mediated food allergy) in adults, the recommended diagnostic approach is primarily clinical and involves an allergy-focused history followed by a trial elimination diet of the suspected allergen for 2–6 weeks, with subsequent reintroduction to observe symptom changes.

No specific diagnostic tests such as skin prick tests or specific IgE antibody blood tests are recommended for non-IgE-mediated food allergy, as these tests are used to identify IgE-mediated allergies.

Alternative diagnostic tests like serum-specific IgG testing, vega test, applied kinesiology, and hair analysis are not recommended for diagnosing food allergy or sensitivities.

Referral to a dietitian with appropriate competencies is advised to ensure nutritional adequacy during elimination and reintroduction phases.

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This content was generated by iatroX. Always verify information and use clinical judgment.